A Pioneer & the first Private Clinic to offer Esketamine Treatment in the UK
London Esketamine Clinic was the first private medical clinic in the UK to offer Esketamine nasal spray (Spravato®), beginning in September 2020.
Following MHRA approval in 2020, Esketamine became a licensed treatment option for adults with moderate to severe treatment-resistant depression — typically defined as depression that has not responded to at least two different antidepressants.
As part of Nurify Medical, our clinic combines innovation with safety, offering this advanced treatment under strict clinical supervision in our Harley Street setting.
Esketamine at a Glance
Who Is Esketamine For?
Esketamine may be suitable for adults diagnosed with treatment-resistant depression.
Every patient undergoes a comprehensive consultant-led psychiatric assessment to confirm diagnosis and determine suitability. We do not offer “quick fixes.” We offer careful, evidence-based treatment pathways tailored to the individual.
Our consultant psychiatrists will guide you through:
- Diagnostic confirmation
- Review of previous treatments
- Risk assessment
- Discussion of alternative options
- Clear explanation of benefits and side effects
Only once suitability is confirmed will treatment begin.
How Esketamine Is Delivered
Esketamine is administered intranasally using a nasal spray device.
However, unlike standard medications, it is never taken at home.
Each session is delivered exclusively within our clinic under the supervision of trained clinicians. During treatment:
- Blood pressure and heart rate are monitored
• Patients remain in clinic for observation
• Clinical staff are present throughout
This structured protocol ensures safety, comfort, and optimal monitoring.
What to Expect During Treatment
Treatment typically follows an induction phase over two months:
- Month 1: Two sessions per week
- Month 2: One session per week
Following this phase, some patients may move to a maintenance schedule, with sessions gradually reduced depending on clinical response.
Regular psychiatric review is essential to ensure sustained improvement and long-term remission.
Patient Journey
Why Patients Choose
London Esketamine Clinic
- First Private Provider of Esketamine in the UK
- CQC Registered Private Clinic
- Registered Private Clinic
- Consultant Psychiatrist–Led Care
- Central location on Harley Street
- Transparent Pricing
Take the first steps today
Book your initial consultation with our expert clinical team.
Quick response — Confidential support — Begin your recovery journey
